منابع مشابه
Discrete versus cumulative dosing in dose-response discrimination studies.
This study describes the results of a 'side-by-side' comparison of two measurement techniques and two dosing regimens in a discrimination study using rats trained to either 10 mg/kg cocaine or 2 mg/kg 3,4-methylenedioxymethamphetamine (MDMA). The measurements employed were either quantal or quantitative; the former an all-or-none correct lever selection measure and the latter a measure of all r...
متن کاملEvening -versus morning- dosing drug therapy for chronic kidney disease patients with hypertension: a systematic review.
BACKGROUND/AIMS There is a strong correlation between non-dipping status and cardiovascular events in chronic kidney disease (CKD) patients. Our study is designed to identify the effect of evening administration of antihypertensive drugs to hypertensive CKD patients. METHODS A comprehensive search of Medline, Embase, the Chinese Biomedical Literature Database, Wanfang Data, Chinese National K...
متن کاملObstetric Pharmacokinetic Dosing Studies are Urgently Needed
Use of pharmacotherapy during pregnancy is common and increasing. Physiologic changes during pregnancy may significantly alter the overall systemic drug exposure, necessitating dose changes. A search of PubMed for pharmacokinetic clinical trials showed 494 publications during pregnancy out of 35,921 total pharmacokinetic published studies (1.29%), from the late 1960s through August 31, 2013. Cl...
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ژورنال
عنوان ژورنال: American Journal of Hypertension
سال: 1996
ISSN: 0895-7061
DOI: 10.1016/0895-7061(96)87758-2